Sermorelin

Stimulates Growth Hormone

$120.00

What is Sermorelin Acetate

  • Type: Peptide hormone analog

  • Class: Growth hormone-releasing hormone (GHRH) analog

  • Sequence: 29 amino acids (1–29 fragment of endogenous GHRH)

    • One-letter amino acid sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂

  • Molecular weight: ~3,373 Da

  • Formulation: Typically as Sermorelin Acetate, which stabilizes the peptide for storage and injection.


 Mechanism of Action

  1. Stimulates Growth Hormone (GH) secretion:

    • Acts on pituitary somatotrophs by binding to GHRH receptors.

    • Increases pulsatile release of endogenous GH, mimicking natural secretion patterns.

  2. Downstream effects:

    • Increased IGF-1 (Insulin-like Growth Factor 1) production in the liver.

    • Promotes protein synthesis, fat metabolism, bone density, and lean body mass.