LYSINE-PROLINE-VALINE

Immunity Enhancer

$120.00

Lysine–Proline–Valine (KPV) peptide is a short tripeptide composed of three amino acids in sequence: lysine (K), proline (P), and valine (V). Despite its small size, it’s biologically interesting and has been studied mainly for its anti-inflammatory and immunomodulatory properties.

What it is

  • Type: Tripeptide

  • Sequence: Lys–Pro–Val (KPV)

  • Origin: It is a naturally occurring fragment derived from α-melanocyte-stimulating hormone (α-MSH), a peptide involved in regulating inflammation and immune responses.

Biological activity

KPV is best known for:

  • Anti-inflammatory effects
    It can reduce the production of pro-inflammatory cytokines (such as TNF-α and IL-6) and help calm overactive immune responses.

  • Immunomodulation
    Rather than broadly suppressing immunity, KPV helps rebalance immune signaling, especially in epithelial tissues.

  • Gut and skin relevance
    Research has focused on its potential role in intestinal inflammation (e.g., inflammatory bowel conditions) and skin inflammation due to its calming effects on immune cells.