IGF-1 LR3

Cellular Growth

$200.00

Product Overview

IG1 is a catalog label commonly used by research-peptide suppliers to refer to IGF-1 LR3, a long-acting analog of insulin-like growth factor-1.
IGF-1 LR3 is engineered for improved stability, bioavailability, and receptor affinity, making it ideal for controlled in-vitro and ex-vivo experiments involving:

  • cellular growth pathways

  • protein synthesis mechanisms

  • tissue repair models

  • metabolic and endocrine-related signaling research

Supplied in lyophilized (freeze-dried) form, IG1 typically comes in a 1 mg, 2 mg, or 10 mg vial, depending on the vendor.


 Scientific Background

IGF-1 is a naturally occurring peptide hormone involved in:

  • cellular growth and differentiation

  • IGF-1 receptor signaling

  • muscle and connective-tissue biology

  • anabolic and metabolic pathways

IGF-1 LR3 is a modified version with two key changes:

  1. Arginine substitution at position 3 (R3) — reduces binding to IGF-binding proteins (IGFBPs).

  2. Extended amino acid chain (83 aa vs. 70 aa) — increases half-life and reduces degradation.

These modifications allow IGF-1 LR3 to remain active much longer in research settings, providing more consistent activity in cell-culture and mechanistic studies.